Accepted on 08 Jun 2021
Submitted on 08 Jun 2021
In Table 1 of Albillos et al. [1] there is no Off-State N = 33 value of NMSS total score and of PDCRS total score.
Table 1
Comparison of participant’s characteristics.
| NOVO-PD N = 19 |
PD N = 35 |
ET N = 19 |
CONTROLS N = 35 |
P-VALUE | ||
|---|---|---|---|---|---|---|
| ON-STATE | OFF-STATE | |||||
| Males (%) | 13 (68) | 24 (69) | 22 (67) | 12 (63) | 11 (31) | 0.01 |
| Age (years)a | 66.9 (8.8) | 64.5 (9.1) | 64.1 (9.0) | 70.8 (6.7) | 61.4 (7.3) | 0.002 |
| Disease duration (years) | 1 (0.6; 3) | 10 (2; 25) | – | 7 (1; 29) | – | – |
| UPDRS-III score | 20 (8; 41) | 24 (5; 49) | 35 (12; 70) | – | – | 0.01 |
| NMSS total score | 42 (24; 86) | 69 (12; 119) | – | – | – | 0.08 |
| PDCRS total score | 74 (58; 112) | 80 (43; 109) | – | – | – | 0.91 |
Values are expressed in medians (interquartile range) otherwise specified a = mean (Standard deviation). Parkinson’s disease (PD) (total sample = 35) measured in the ON state (ON-PD) (n = 35) and OFF state (OFF-PF), (n = 33); ET = Essential Tremor; UPDRS = Unified Parkinson’s disease Rating Scale; NMSS = Non motor symptoms severity score: PDCRS = Parkinson’s disease cognitive rating scale. Data were compared using the ANOVA test.
In Table 2, the values of α-Synuclein are quoted in ng/ml. The label of the first cell of the last row is ‘Pairwise comparisons’ and should read (1) vs. (5), (2) vs. (4), and (3) vs. (5) (second cell), (1) vs. (2) and (1) vs. (3) (third cell) and (1) vs. (2), (1) vs. (4), and (3) vs. (4) (fifth cell).
Table 2
Plasma α-synuclein quantitation (ng/ml) stratified by age and gender.
| GROUPS | α-SYNUCLEIN (ng/ml) MEAN ± SD |
p-VALUE | α-SYNUCLEIN (ng/ml) MEAN ± SD |
P-VALUE | ||
|---|---|---|---|---|---|---|
| MEN (n) |
WOMEN (n) |
<66 YEARS OLD (n) |
≥66 YEARS OLD (n) |
|||
| CONTROL (1) | 158.40 ± 102.95 (11) |
177.12 ± 86.53 (24) |
0.57 | 174.81 ± 94.85 (25) |
162.32 ± 84.18 (10) |
0.71 |
| ON-PD (2) | 112.30 ± 56.63 (23) |
111.08 ± 40.45 (10) |
0.95 | 125.76 ± 56.77 (17) |
97.24 ± 42.45 (16) |
0.11 |
| OFF-PD (3) | 128.64 ± 46.37 (21) |
127.26 ± 29.16 (10) |
0.92 | 137.40 ± 43.43 (16) |
118.37 ± 37.40 (15) |
0.20 |
| NOVO-PD (4) | 91.92 ± 35.28 (13) |
131.25 ± 50.01 (6) |
0.06 | 90.21 ± 26.38 (7) |
112.58 ± 49.91 (12) |
0.21 |
| ET (5) | 79.74 ± 32.11 (12) |
143.73 ± 71.89 (6) |
0.08 | 54.33 ± 1.95 (2) |
106.92 ± 56.94 (16) |
|
| Pairwise comparisons | (1) vs. (5)(2) vs. (4)(3) vs. (5) | (1) vs. (2)(1) vs. (3) | <0.05* | (1) vs. (2)(1) vs. (4)(3) vs. (4) | n.s | <0.05* |
SD = Standard deviation. Age was stratified based on the median distribution of the total sample. * Pairwise intra-group comparisons as indicated in each column; n.s = not significant.
The correct tables are included here.
This information was not included correctly in the final versions sent by the authors.
The authors have no competing interests to declare.
Albillos SM, Montero O, Calvo S, Solano B, Trejo JM, Cubo E. Can Plasma α-Synuclein Help Us to Differentiate Parkinson’s Disease from Essential Tremor? Tremor and Other Hyperkinetic Movements. 2021; 11(1): 20, pp. 1–8. DOI: https://doi.org/10.5334/tohm.600