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Case Reports

Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease

Authors:

Gwanhee Ehm,

Department of Neurology, National Medical Center, Seoul, KR
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Han-Joon Kim,

Department of Neurology, College of Medicine, Seoul National University, Seoul; Movement Disorder Center, Seoul National University Hospital, Seoul; Parkinson Study Group, Neuroscience Research Institute, College of Medicine, Seoul National University, Seoul, KR
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Beomseok Jeon

Department of Neurology, College of Medicine, Seoul National University, Seoul; Movement Disorder Center, Seoul National University Hospital, Seoul; Parkinson Study Group, Neuroscience Research Institute, College of Medicine, Seoul National University, Seoul, KR
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Abstract

Background: Myoclonus and encephalopathy are unusual in patients with Parkinson’s disease (PD).

Case report: We describe the case of a 59-year-old male with PD who developed myoclonus and encephalopathy. Underlying hypothyroidism was revealed after admission and treated with levothyroxine. Myoclonus and encephalopathy were completely resolved following thyroid hormone replacement.

Discussion: Hypothyroidism can cause reversible myoclonus and encephalopathy along with unusual aggravation of parkinsonism symptoms in patients with PD.

How to Cite: Ehm G, Kim H-J, Jeon B. Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease. Tremor and Other Hyperkinetic Movements. 2017;7:505. DOI: http://doi.org/10.7916/D8BP0F9F
Published on 19 Oct 2017.
Peer Reviewed

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