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Reading: Sertraline-induced Hemichorea

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Case Reports

Sertraline-induced Hemichorea

Authors:

Emilia M. Gatto ,

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Victoria Aldinio,

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Virginia Parisi,

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Gabriel Persi,

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Gustavo Da Prat,

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Maria Bres Bullrich,

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Pilar Sanchez,

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Galeno Rojas

Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, AR
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Abstract

Background: Hemichorea–hemiballism is a syndrome secondary to different etiologies. Drug-induced hemichorea is a rare syndrome related to selective serotonin reuptake inhibitors. To the best of our knowledge, no previous cases of hemichorea associated with sertraline have been reported.

Case Report: A 65-year-old female noticed hemichorea 1 week after initiation of sertraline. After extensive investigations, other causes of hemichorea were excluded. Hemichorea remitted after sertraline withdrawal.

Discussion: In our patient, temporal association and the negative clinical assessment supported a diagnosis of likely drug-induced involuntary movement. We hypothesized that enhanced serotonergic transmission in the ventral tegmental area or nigrostriatum may be involved in sertraline-induced hemichorea.

How to Cite: Gatto EM, Aldinio V, Parisi V, Persi G, Da Prat G, Bullrich MB, et al.. Sertraline-induced Hemichorea. Tremor and Other Hyperkinetic Movements. 2017;7:518. DOI: http://doi.org/10.7916/D8XK999F
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Published on 18 Dec 2017.
Peer Reviewed

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