Thalamic Deep Brain Stimulation for Orthostatic Tremor

  • Toby C. Yaltho
  • William G. Ondo


Background: Orthostatic tremor is an uncommon disorder manifest by high frequency, low amplitude leg tremor upon weight bearing. Treatment with oral tremor agents is inconsistent and usually not satisfactory.

Methods: We implanted bilateral ventralis intermedius nuclei deep brain stimulators into an 82-year-old male with refractory orthostatic tremor.

Results: The patient had a marked subjective and objective improvement in leg and arm tremor, mainly manifested by an improved ability to stand.

Discussion: Bilateral thalamic deep brain stimulation may be considered in refractory cases of orthostatic tremor.