Characterization and Treatment of Unilateral Facial Muscle Spasm in Linear Scleroderma: A Case Report

  • Fabio Osvaldo Danisi
  • Emma Guidi


Background: Linear scleroderma has been associated with muscle spasms ipsilateral to skin lesions.  Typically, spasms are generated by trigeminal innervated muscles, leading to hemi-masticatory spasm (HMS).

Case Report: We report a case of linear scleroderma associated with spasm of muscles innervated not only by the trigeminal, but also by the facial nerve.

Discussion: We review the patient’s successful treatment with incobotulinumtoxinA, a formulation of botulinum toxin that has not been reported for use in this condition.